GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | trans | rs4272382 | 1 | rs4272382 | chr8:8433488 | R3HCC1 | chr8:23145612-23153791:+ | -0.57 | -6.45 | 3.41E-10 | Response to cytidine analogues (gemcitabine) |
| BLCA | trans | rs1056667 | 1 | rs4713006 | chr6:26519872 | ZNF322B | chr9:99957633-99961910:- | 0.45 | 7.91 | 2.73E-14 | Educational attainment |
| BLCA | trans | rs1056667 | 1 | rs4713008 | chr6:26538268 | ZNF322B | chr9:99957633-99961910:- | 0.46 | 8.01 | 1.35E-14 | Educational attainment |
| BLCA | trans | rs6600671 | 1 | rs4844607 | chr1:121184059 | NBPF14 | chr1:148003643-148346791:- | -0.29 | -6.3 | 8.24E-10 | Hip geometry |
| BLCA | trans | rs6600671 | 1 | rs4844616 | chr1:121171208 | NBPF14 | chr1:148003643-148346791:- | 0.29 | 6.43 | 3.86E-10 | Hip geometry |
| BLCA | trans | rs1056667 | 1 | rs4871 | chr6:26545632 | ZNF322B | chr9:99957633-99961910:- | 0.46 | 8.01 | 1.42E-14 | Educational attainment |
| BLCA | trans | rs4889911 | 1 | rs4889910 | chr17:77839795 | RPL13AP3 | chr14:56232963-56234434:+ | 0.37 | 6.54 | 2.01E-10 | Electroencephalogram traits |
| BLCA | trans | rs4889911 | 1 | rs4889910 | chr17:77839795 | RPS26 | chr12:56435686-56438005:+ | -0.4 | -6.45 | 3.32E-10 | Electroencephalogram traits |
| BLCA | trans | rs59336 | 1 | rs545076 | chr12:115119903 | LOC100130932 | chr19:14599758-14600688:+ | 0.38 | 6.5 | 2.54E-10 | Colorectal cancer |
| BLCA | trans | rs59336 | 1 | rs545076 | chr12:115119903 | RPL19P12 | chr7:102781717-102782850:- | 0.39 | 6.55 | 1.86E-10 | Colorectal cancer |
| BLCA | trans | rs2786111 | 1 | rs550098 | chr1:197297408 | CSNK1A1 | chr5:148872949-148931007:- | -0.28 | -5.95 | 5.89E-9 | Lupus nephritis in systemic lupus erythematosus |
| BLCA | trans | rs62295889 | 1 | rs57066147 | chr4:12578947 | KRTAP13-1 | chr21:31768392-31769136:+ | 0.15 | 6.43 | 3.77E-10 | Obesity-related traits |
| BLCA | trans | rs2786111 | 1 | rs643025 | chr1:197298860 | CSNK1A1 | chr5:148872949-148931007:- | 0.28 | 6.01 | 4.33E-9 | Lupus nephritis in systemic lupus erythematosus |
| BLCA | trans | rs1056667 | 1 | rs6456733 | chr6:26566804 | ZNF322B | chr9:99957633-99961910:- | 0.46 | 8.07 | 9.07E-15 | Educational attainment |
| BLCA | trans | rs1056667 | 1 | rs6456734 | chr6:26566965 | ZNF322B | chr9:99957633-99961910:- | 0.46 | 8.07 | 9.07E-15 | Educational attainment |